Pregnancy Vaccine

What is Pregnancy Vaccine?

It is a vaccine made to facilitate the stimulation of the inner lining of the uterus, making it more prone to retain the embryo. Thanks to the pregnancy vaccine, especially in vitro fertilization treatment, the embryo's attachment to the uterus and the chance of a live baby can be increased.

However, it would be more appropriate to apply the method to patients with thin uterine lining. Pregnancy vaccine, which is the popular method of recent years, has been used in some clinics for a while. However, it should not be explained to patients as if it is a miraculous method. The aim is to stimulate the inner lining of the uterus to ensure that the embryo adheres better. For this purpose, the treatment is started by giving a drug that stimulates the immune system to the patient, and after 2-3 weeks, the cells that will repair the inner lining of the uterus are separated from the blood taken from the patient, they are reproduced in a special medium in the laboratory environment, and different growth factors and hormones are secreted into it. It is aimed to obtain a better place for the embryo by giving these cells into the uterus before embryo transfer.

In some cases, even if the embryos develop healthy, there is no attachment due to problems in the uterus. In such cases, uterine lining problems are predicted as the most important reason. Thinning of the inner lining of the uterus for any reason, adhesion, mass (polyp, fibroid) and inflammation should be evaluated with a uterine film and examination, and if any, these problems should be eliminated by surgery. After these conditions are ruled out, this vaccine can be applied due to the adhesion problem in patients who do not have adhesion and miscarriage despite the good quality embryo given.

How is the Pregnancy Vaccine Applied?

Before the egg collection day, the patient's own blood is taken from the patient and the reparative cells in this blood are separated from this blood. Then, these cells are multiplied by culturing in special containers and some supporting hormones and factors are added. The liquid obtained in this way is called pregnancy vaccine.

Eggs collected from the woman are brought together with the sperm collected from the man in the laboratory and fertilized. The healthiest embryos obtained in this way are selected and the transfer day is reached.

1-2 days before the transfer of embryos to the uterus, the most thickened place of the uterus for transfer is determined under ultrasound guidance. The pregnancy vaccine created from the woman's blood is given into the uterus after the cervix is ​​washed. With the pregnancy vaccine, it has been determined that the uterus can allow the embryos to be transferred later to settle and develop much more easily. It is thought that with this vaccine, the embryo can hold much more easily.

It is observed that embryos transferred to the intrauterine environment, which have been vaccinated for pregnancy, adhere to the uterus at a higher rate and pregnancy rates increase in parallel with this.

Since it is a newly developed method, its results are being evaluated. However, it can be recommended for couples who have problems with the attachment of the embryo in the uterus, especially in IVF treatments.