What is Dual Stimulation?
Ovarian reserve is the capacity of the ovaries to produce egg cells, which are capable of being fertilized. We, as reproductive health specialists, try to help with the reduction of ovarian reserve, which occurs due to many physiological or environmental reasons, with various methods developed. Thousands of couples apply to IVF centers every year with the desire to have children at different ages due to the decrease in ovarian reserves.
While every woman is still in the mother's womb, the precursor egg cells begin to develop and each individual is born with a different number of egg cells. These eggs decrease and deplete as age progresses from puberty to menopause. The rate of exhaustion is different for each woman. Environmental factors and genetic factors also affect the time to menopause.
Decreased ovarian reserve at an early age is a challenging process for women. Family history of early menopause, genetic factors, chocolate cysts, cancer, radiation therapy (radiotherapy), chemotherapy, previous ovarian surgeries, environmental factors may reduce ovarian reserve. The aim of women with low ovarian reserve is to collect eggs without wasting time. It may be necessary to collect eggs more than once to increase the chances of conception. In the past, egg collection can be done once in each menstrual cycle, but thanks to the Dual Stimulation method, egg collection can be performed 2 times in the same month.
Since the time limit is very important in a group of patients who will be treated for cancer, Random Start (random start) or Dual Stimulation methods were developed with this patient group, and then this treatment option was extended to all patient groups with reduced reserve.
To whom do we recommend the Dual Stimulation method:
1) Those who have a family history of early menopause and low AMH hormone
2) For those whose ovarian reserve has decreased as a result of previous ovarian cyst surgery
3) Women with low ovarian reserve due to genetic factors
4) For those with autoimmune thyroid diseases
5) Women with reduced ovarian reserve due to chocolate cysts
6) Before chemotherapy or radiotherapy in women diagnosed with cancer
While every woman is still in the mother's womb, the precursor egg cells begin to develop and each individual is born with a different number of egg cells. These eggs decrease and deplete as age progresses from puberty to menopause. The rate of exhaustion is different for each woman. Environmental factors and genetic factors also affect the time to menopause.
Decreased ovarian reserve at an early age is a challenging process for women. Family history of early menopause, genetic factors, chocolate cysts, cancer, radiation therapy (radiotherapy), chemotherapy, previous ovarian surgeries, environmental factors may reduce ovarian reserve. The aim of women with low ovarian reserve is to collect eggs without wasting time. It may be necessary to collect eggs more than once to increase the chances of conception. In the past, egg collection can be done once in each menstrual cycle, but thanks to the Dual Stimulation method, egg collection can be performed 2 times in the same month.
Since the time limit is very important in a group of patients who will be treated for cancer, Random Start (random start) or Dual Stimulation methods were developed with this patient group, and then this treatment option was extended to all patient groups with reduced reserve.
What is Dual Stimulation Therapy?
During IVF treatments, the number of eggs and, accordingly, the number of embryos are the most important factors that increase success. That's why we use the method we call embryo pooling for our patients whose reserves are low. With the dual stimulation treatment option, a kind of accelerated pool system is applied and the maximum number of embryos is reached quickly. Thus, time is saved. 3 to 5 days after the first egg collection, an ultrasonographic examination is performed and preparations for the second egg collection process are started. The eggs are tried to be grown with a protocol similar to the first collection and these developing eggs are also collected. In this protocol, embryo transfer is performed in the next menstrual cycle.To whom do we recommend the Dual Stimulation method:
1) Those who have a family history of early menopause and low AMH hormone
2) For those whose ovarian reserve has decreased as a result of previous ovarian cyst surgery
3) Women with low ovarian reserve due to genetic factors
4) For those with autoimmune thyroid diseases
5) Women with reduced ovarian reserve due to chocolate cysts
6) Before chemotherapy or radiotherapy in women diagnosed with cancer
