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Can PRP (Platelet Rich Plasma) Application Be a New Hope for Decreased Ovarian Reserve?

All female babies have around 2 million eggs in their ovaries when they are born, and this seemingly huge warehouse dwindles to around 400.000 by the time of puberty. An average of 1000 eggs are lost each month. From the mid-30s onwards, both the number of eggs and the quality of the eggs have deteriorated significantly. Towards the middle of the 40s, the ovarian stores are almost non-existent. This process is a process that develops normally in the ovaries of women, followed by the menopausal period.

In a normal menstrual cycle, we observe a certain number of eggs each month with ultrasound, and one of them matures, cracks and passes into the tube, this process is called ovulation. While one of every 30-2 eggs in a 3-year-old woman is chromosomally correct, this ratio decreases to one in 40-5 eggs at the age of 6.

In order for pregnancy to occur in normal ways and to achieve pregnancy in in vitro fertilization applications, egg drafts should be displayed in the ovaries ultrasonographically. Each egg that will develop at this stage will have a significant contribution to pregnancy outcomes. At this stage, in the last year in the world PRP It has come to the fore that the procedure may be beneficial on ovarian deposits.

“PRP” (Platelet Rich Plasma) or also known as Platelet Rich Plasma is a method prepared from one's own blood and used to stimulate and regulate healing in many areas of medicine. With the help of dozens of PRP preparation kits in use, 10-60 ml of blood is taken from the patient, this blood is separated with disposable special filters and centrifuge devices and the unwanted parts are removed. The separated 2-6 ml portion contains PRP. The idea that the presence of some growth factors in this serum may be beneficial when applied to the patient group with reduced ovarian deposits has come to the fore. For this purpose, injecting it into the ovary can enable some cells that are silent in the ovaries to become active within a few months after the procedure. Since there are very limited scientific studies in the world, it is useful to be cautious about giving very clear information about this method and making big promises to patients. However, it should be taken into account that ovarian activity can be achieved in a limited number of data as a result of short-term applications in the world. For this reason, this method, which appears as a promising treatment application for the patient group with reduced egg stores, has also entered the field of interest of our clinic.

Dr. Ozan Ozolcay

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